Institution
Institute of Neuroimmunology of the Slovak Academy of Sciences
Recent research
- Health & Medicine
OBJECTIVES: To determine the association between Multiple Sclerosis (MS) and Degenerative Spine Disease (DSD) and the subsequent utilization of interventional pain (IVP) procedures and spine surgery. DESIGN: A retrospective, active comparator cohort study using TriNetX. Adults wi...
- Health & MedicineOpen access
EBV reactivation priming of the peripheral immune system in multiple sclerosis relapse
Despite decades of research, the cellular and molecular events preceding multiple sclerosis (MS) relapse remain incompletely understood. Here, in this observational study of longitudinal blood samples from patients with relapsing-remitting MS, we used single-cell RNA sequencing,...
- BiologyOpen access
Background Diabetic peripheral neuropathy (DPN) is a common complication of type 2 diabetes mellitus (T2DM). Neurofilament light chain (NfL) is a circulating marker of neuroaxonal injury, but its interpretation may be influenced by age and renal function. Objective To evaluate th...
- Health & MedicineOpen access
<title>Abstract</title> Background and Objectives Multiple sclerosis (MS) is a chronic inflammatory disease characterized by demyelinating lesions in the central nervous system. While animal models have provided valuable insights into lesion development, human-based studies—parti...
- Health & Medicine
Background: Antibody-mediated rejection (AMR) is the main driver of late kidney allograft loss. Anti-HLA donor-specific antibodies (DSA) are strongly associated with AMR. However, 30-60% of DSA + patients do not develop AMR, raising the possibility of local tissue adaptations to...