Institute of Molecular Bioimaging and Physiology

Radiolabelled Antisense miRNA Oligonucleotides for Molecular Imaging and Therapeutic Applications

Background/Objectives: MicroRNAs (miRNAs) are small non-coding RNAs (20–24 nucleotides) that regulate post-transcriptional gene expression and are involved in key biological processes, including proliferation and apoptosis. Dysregulation of miRNA expression is associated with num...

TSPO PET selectively detects the denervated skeletal muscle district remodeling after experimental peripheral nerve injury

Abstract Background Peripheral nerve injury induces inflammatory and stress-related remodeling in downstream skeletal muscle before overt atrophy develops, yet non-invasive approaches capable of detecting and anatomically localizing early muscle involvement remain limited. The 18...