Institute of Life Sciences

Design, synthesis, SAR, in silico and in vitro evaluation of 1, 3, 4-oxadiazole derivatives against breast cancer

The 1,3,4-oxadiazole scaffold is well recognized for its anticancer potential. Based on our previous work, we designed and synthesized nine 1,3,4-oxadiazole derivatives (R1–R9) via Schiff base formation followed by cyclization. The compounds were characterized by FT-IR, ¹H NMR, a...

K9HeartCircDB: a circRNA atlas of tachypacing-induced canine dilated cardiomyopathy

ABSTRACT Cardiovascular disease (CVD) remains a leading cause of death worldwide. Dilated cardiomyopathy (DCM), a major cause of heart failure (HF), exhibits ventricular dilation, impaired systolic/diastolic function, arrythmias, and adverse cardiac remodeling. While genetic caus...

Highlights from the 17th Japan Bioanalysis Forum Symposium

The 17th Japan Bioanalysis Forum Symposium was held in Himeji, Japan, in March 2026. Under the theme "Unlock Scientific Potential: Future of Bioanalytical Expert," the symposium provided a comprehensive forum to share and discuss the latest scientific, technological, and regulato...