Institute of Human Genetics

We don't care how much you sweat: An epistemic framework for behavioral and brain science laboratory infrastructure

For decades, behavioral and brain research has advanced by isolating single variables or brain regions to study behavior and performance. However, it has become increasingly clear that reductionist methods struggle to capture the complex, dynamic, and context-dependent nature of...

Whole-Genome Sequencing Identifies Potentially Causative Variants in SOX30, AKAP4, and RNF220 in Non-Obstructive Azoospermia

More than 70% of non-obstructive azoospermia (NOA) cases remain idiopathic, and the underlying genetic causes need to be investigated. In this study, we aimed to identify genes and variants associated with the etiology of NOA. Two NOA patients from consanguineous families, with n...

No association between smoking and obstructive sleep apnea in men: evidence from middle-aged adults followed into later life

RATIONALE: The relationship between smoking and obstructive sleep apnea (OSA) remains unclear. Observational findings have been inconsistent, and associations may vary depending on study population, design, measurements. OBJECTIVES: To evaluate the cross-sectional and longitudina...

Life-threatening fetal goiter: diagnosis and outcomes in four consecutive cases with critical appraisal—why this diagnosis is not obviously trivial

BACKGROUND: The diagnosis of a fetal goiter constitutes a potentially life-threatening in utero condition for the fetus. Even with early diagnosis and close therapy with highly specialized interdisciplinary management, the prognosis remains poor. We discuss diagnostic and therape...

KSR2 is a novel oncogene in TAL1 subtype of T-cell acute lymphoblastic leukemia with potential clinical and prognostic implications - Supplementary Methods

Supplementary Materials and Methods for "KSR2 is a novel oncogene in TAL1 subtype of T-cell acute lymphoblastic leukemia with potential clinical and prognostic implications" accepted for publication in Haematologica (2026) The published article includes an abbreviated Methods sec...

KSR2 is a novel oncogene in TAL1 subtype of T-cell acute lymphoblastic leukemia with potential clinical and prognostic implications - Supplementary Methods

Supplementary Materials and Methods for "KSR2 is a novel oncogene in TAL1 subtype of T-cell acute lymphoblastic leukemia with potential clinical and prognostic implications" accepted for publication in Haematologica (2026) The published article includes an abbreviated Methods sec...