Institute of Experimental Medicine

Crystal Structure of 1,1-Dimethyl-3-(quinolin-2-yl)urea and 3-(Isoquinolin-1-yl)-1,1-dimethylurea

The crystal structures of two isomeric urea derivatives—1,1-dimethyl-3-(quinolin-2-yl)urea (1) and 3-(isoquinolin-1-yl)-1,1-dimethylurea (2)—have been investigated by single-crystal X-ray diffraction. These compounds differ in the relative position of the heterocyclic nitrogen at...

The Probiotic Strain Hafnia Alvei HA4597 and Its Protein Extract Selectively Activate Membrane Digestive Enzymes of Intestinal Cells in Mice

Oral supplementation of the Hafnia alvei (H. alvei) HA4597 probiotic strain has been shown to reduce appetite, body weight and fat content in overweight humans and obese mice. However, it remains unknown if H. alvei may also influence the gut digestive function. Thus, in the pres...