Institute of Cytology and Genetics

Cerebral dopamine neurotrophic factor (CDNF) affects hippocampal neuroplasticity and fear memory in rats

The role of CDNF in modulating learning and memory remains largely unexplored. Here, hippocampal CDNF overexpression significantly accelerated extinction of contextual and cued fear memory in rats. Molecularly, overexpressed CDNF was retained in the ER and upregulated mRNA levels...

The Genetic Diversity of Old and Modern Accessions of Glycine max Revealed by Genotyping-by-Sequencing (GBS)

Soybean (Glycine max (L.) Merr.) is one of the most widely cultivated grain legumes worldwide. A genetic analysis of soybean samples around the world is essential for effective breeding programs and the development of genomic and marker-assisted selection. This study investigated...

Machine Learning-Guided Stress Atlases Reveal Co-Expression Rewiring and Divergent Cellular Deployment of Abiotic Stress Programs in Rice and Wheat

Abiotic stress limits cereal productivity, yet whether conserved stress-responsive genes retain similar transcriptional network organization and cellular deployment across cereal species remains unknown. Here, we developed a machine learning-guided comparative framework to integr...