Institute of Child Health

Prevalence of Autoimmune Comorbidities in Type-1 Diabetes: A Hidden Burden in the Pediatric Population

Objectives: Type 1 diabetes mellitus (T1DM) is an autoimmune disorder frequently associated with other autoimmune conditions such as autoimmune thyroid disease and coeliac disease, largely due to shared human leukocyte antigen susceptibility and immune dysregulation. This study e...

EP464 - ECE_2010 - Hyperphagia severity in adult patients with Bardet-Biedl Syndrome-a mixed-methods cross-sectional study in the United Kingdom

Background Bardet-Biedl Syndrome (BBS) is a rare genetic disease frequently associated with hyperphagia, an insatiable feeling of hunger, persistent food-seeking behaviours and abnormal food intake. This can have behavioural, emotional, social and health consequences, and may lea...

Minimally verbal status in children with intellectual disability of genetic origin – prevalence, functional impact and relationship with motor skills: evidence from the IMAGINE-ID cohort

Abstract Background Up to a third of autistic children do not develop functional speech and remain minimally verbal (MV) beyond the age of 5, yet little is known about the clinical characteristics of this group. Less still is known about the prevalence or impact of MV status in c...

Protocol for a feasibility study of a self-help resource based on the principles of cognitive behavioural therapy to reduce needle fear in young people aged 11- to 16 years

Abstract Background Needle fear affects up to half of all young people, with the potential to impede their accessing and acceptance of healthcare interventions. There is presently a lack of accessible self-help resources available to support young people in managing needle-based...

Transforming thalassaemia care in India through virtual capacity building: Evolution of a national training initiative using extension for community healthcare outcomes model

BACKGROUND AND OBJECTIVES: India has one of the world's highest burdens of thalassaemia, with 10,000-15,000 births annually and a carrier prevalence of 3%-4%. Services for prevention and comprehensive care remain fragmented, especially in rural regions. To address gaps in provide...