Institute of Bioorganic Chemistry, Polish Academy of Sciences

Cannabichromene-based imidazolium salts as antibacterial agents: microwave-assisted synthesis and biological evaluation

The increasing prevalence of antimicrobial resistance highlights the urgent need for new antimicrobial agents with improved efficacy and safety profiles. Cannabichromene (CBC) is a non-psychoactive phytocannabinoid with reported antibacterial activity, but its limited chemical st...

Generation of transgene-free MtABCG46 mutants in Medicago truncatula using CRISPR/Cas9

ATP-binding cassette (ABC) transporters form one of the largest and most functionally diverse families of membrane proteins in plants, with members of the ABCG subfamily playing central roles in the transport of specialized metabolites and stress adaptation. In legumes functional...