Institute of Bio-Resources and Sustainable Development

Targeting IL-10–mediated JAK–STAT signaling in cervical cancer: integrative network pharmacology, molecular docking, and experimental validation of Zerumbone

This study investigated the potential interaction between zerumbone (ZER) and interleukin-10 (IL-10) using molecular docking and molecular dynamics (MD) simulations. Computational analyses suggested a stable association of ZER with a functionally relevant region of IL-10. Gene On...

Genomic and molecular insights into AMR, virulence, and toxin of Shiga toxin–producing Escherichia coli isolated from local curd foodborne outbreak in Manipur

This study reports the isolation, characterization, and genome analysis of Escherichia coli isolated from curd, revealing potential pathogenic and multidrug-resistant characteristics.15 individuals who consumed the suspected contaminated local curd developed symptoms included acu...