Institute of Animal Physiology of the Slovak Academy of Sciences

Modulatory Effect of Postbiotic Substances (Enterocins-like) on T-Cell-Mediated Immune Response in Trichinella spiralis-Infected Mice

Postbiotic substances produced by beneficial/probiotic strains can modulate host immunity and confer health benefits. This study evaluated immunomodulatory and antiparasitic effects of the postbiotics Enterocin M and Durancin-like, as well as their producing bacteria in mice expe...

TEAD4 Regulates apical domain homeostasis and cell-positioning to maintain the trophectoderm lineage during mouse blastocyst development

Abstract In mammalian preimplantation embryos, distinct cell lineages occupy defined spatial niches. The outer trophectoderm (TE) forms an epithelial monolayer surrounding the inner cell mass (ICM) and blastocyst cavity. In mice, the Tead4 gene encodes a polarity-dependent transc...