Institute for Molecular Bioscience

Genome-wide synthetic lethality screen of Bam complex-associated genes in Escherichia coli

Abstract Biogenesis of the bacterial outer membrane is key to bacterial survival and antibiotic resistance. Central to this is the β-barrel assembly machine (Bam) complex and its associated chaperones, which are responsible for transport, folding and insertion of outer membrane p...

Discovery of a New Triterpenoid and Chemical Profiling of Mudjala (Barringtonia acutangula), an Australian Indigenous Medicinal Plant

Mudjala bark, prepared from Barringtonia acutangula, is an Australian Aboriginal medicine traditionally used for pain relief, and previous studies have associated its activity with triterpenoid-rich fractions. However, the low-molecular-weight triterpenoids, which were major chro...