Institute for Medical Research and Occupational Health

Comparative Toxicological Profiling Reveals Divergent Redox, Mitochondrial, and Cellular Toxicity to Structurally Diverse Opioids

Opioid neurotoxicity is increasingly associated with oxidative stress, mitochondrial dysfunction, and DNA damage; however, direct mechanistic comparisons among structurally diverse opioids remain scarce. We comparatively evaluated morphine, codeine, heroin, buprenorphine, and met...

Sociodemographic correlates of perceived COVID-19 impact on movement behaviors in Croatian school-aged children

Abstract Background Levels of physical activity (PA), sedentary behavior (SB), and sleep, as important determinants of children’s health and weight status, may have been significantly affected by the COVID-19 pandemic. This cross-sectional study aimed to determine factors associa...

Effect of Isothermal Heat Treatment on Oregonin Content in Black Alder Bark Extract

Black alder (Alnus glutinosa (L.) Gaertn.) wood is characterized by rapid and frequently non-uniform color changes after felling and during hydrothermal processing. These changes are largely associated with extractive compounds, among which oregonin, a phenolic diarylheptanoid gl...