Institut universitaire de cardiologie et de pneumologie de Québec

Ultraprocessed Food Intake and Adiposity, Vascular Brain Injury, and Cognition in Middle-Aged Adults

Importance Ultraprocessed foods (UPFs) account for a substantial and increasing proportion of dietary intake in Canada. Although UPFs are consistently associated with adiposity and cardiometabolic disease, their associations with subclinical vascular brain injury (VBI) and cognit...

Optimizing HIV testing uptake among pregnant women in Burkina Faso: machine learning prediction and scenario-based intervention simulations using 2021 Demographic and Health Survey data

HIV testing uptake among pregnant women remains a public health priority in Burkina Faso. This study aimed to identify and rank key predictors of HIV testing uptake using machine learning (ML) approaches and to estimate potential gains under scenario-based intervention simulation...

Impact of Primary Health Care Reforms in Quebec’s Health Care System: A Systematic Review

Introduction: Primary health care (PHC) reforms in Quebec between 2000 and 2023 aimed to improve accessibility, continuity, efficiency, and equity through organisational transformation, notably the Family Medicine Groups (FMGs), centralised waiting lists (Guichets d’accès), the a...

The impact of physical activity and exercise timing on metabolic health among individuals at high risk of type 2 diabetes

The timing of physical activity and exercise has been suggested to play a role in metabolic health. This narrative review synthesises current evidence on the impact of habitual physical activity and exercise timing on glucose homeostasis and insulin sensitivity, blood lipids and...

Cross-sectional evaluation of anthropometric measures vs MRI-measured visceral and hepatic fat in a Canadian cohort

Abstract Context Accurate assessment of excess body fat and its cardiometabolic risk is essential in clinical and epidemiologic research. Body mass index (BMI), although widely used, does not capture visceral or ectopic fat. Objective To evaluate how anthropometric measures—BMI,...

Impact of respiratory syncytial virus immunization in older adults: the importance of a valid burden estimation

ABSTRACT Introduction In the province of Québec, Canada, a respiratory syncytial virus (RSV) immunization program restricted to seniors residing in long-term care facilities (LTCF) and those aged ≥75 years from private senior residences (PSR) was implemented in Fall 2024, with ap...

Germline variants affect lung-to-tumor transcription dynamics and NSCLC outcomes

The influence of germline genetics on the molecular transition from lung to tumor and different transcriptional patterns of tumors remains underexplored. Additionally, little is known about the genetic contributions to lung cancer relapse and mortality following surgery. The tran...