Institut Pasteur de Bangui

Limitations of routine hepatitis E virus diagnosis in Central African Republic: a comparative evaluation of serological and molecular assays

In the Central African Republic (CAR), data on the disease burden of hepatitis E virus (HEV) infection are limited despite recurrent epidemics. HEV is not routinely tested for in cases of elevated transaminases. Our objective was to evaluate the sensitivity and the specificity of...

ViroSeek: a viral detection pipeline for second-generation sequencing

Abstract Arbovirus emergences represent a rising public health issue and are exacerbated by climate change and globalization. Virome analysis has become a key approach for monitoring and managing infectious diseases, yet existing tools often remain technically complex and inacces...