Institut National de la Recherche Agronomique du Niger

Deciphering the genomic signatures of climate vulnerability across 77 sheep breeds

Abstract Among domesticated species, sheep ( Ovis aries ) have achieved a wide geographic distribution due to their mobility, rusticity and ability to adapt to diverse environments and climatic conditions. Here, we characterise the genome-wide diversity of >1,000 sheep representi...

Isolation, in vitro acetylcholinesterase inhibitory activity, molecular docking, and in silico ADME analysis of compounds from Cadaba farinosa roots

Three undescribed compounds were isolated ( 2 , 3 , 5 ) from the roots of Cadaba farinosa Forssk. with twelve known metabolites. In addition, three compounds ( 1 , 4 , 6 ) previously known only from synthetic sources were isolated from the extract and, to our knowledge, have not...

Revealing archaeological olive diversity: insights from stone geometric morphometrics, experimental charring, and varietal identification (Port-la-Nautique, France, Roman period)

The cultivated olive tree, domesticated in the Levant by the mid-5th millennium BCE, spread westward across the Mediterranean to reach southern France by 600 BCE. Although geometric morphometrics applied to archaeological olive stones has provided insights into this diffusion, mo...

A methodological framework for the standardised evaluation of olive genetic resources: GEN4OLIVE harmonized protocols

Background Olive ( Olea europaea L.) breeding initiatives rely heavily on the extensive and correct characterisation of genetic resources to successfully achieve their goals, such as addressing climate change and emerging diseases challenges. However, the historical lack of stand...