Institut Mondor de Recherche Biomédicale

Toward actionable biomarkers in psychiatry: a collaborative roadmap for precision clinical trials. An ACNP position paper

Abstract Psychiatric drug development remains constrained by diagnostic heterogeneity, insufficient and inconsistent drug response, high placebo response rates, and the absence of validated biomarkers that can reliably guide patient stratification, trial design, and regulatory de...

Consensus Definition for Community-acquired Pneumonia in Children Using a Delphi Approach

Background: Although community-acquired pneumonia (CAP) is one of the most common infections in children, no standardized criteria for diagnosis exist. The objective of this study was to develop expert consensus for the diagnosis of pediatric CAP in countries with a high level of...

Detection of a Nirsevimab-Resistant RSV-B Variant (F:K68Q) in an Adult with Severe Infection

Respiratory syncytial virus (RSV) is recognized as a major cause of severe disease in adults, particularly those having cardiorespiratory comorbidities or immunosuppression. The recent deployment of monoclonal antibodies targeting the prefusion F protein could be used in the futu...