Institut d'Investigació Biomèdica de Girona

Natural History of Rare Tumor Risk Syndromes: A Scoping Review to Inform Cost-Effectiveness Models

Background Hereditary cancer syndromes account for approximately 10% of all cancers. Many of these, classified as rare tumor risk syndromes (RTRS), lack comprehensive data on natural history, lifetime cancer risk, and the long-term impact of surveillance. These evidence gaps limi...

Incidence trends and five-year survival of multiple myeloma and other plasma cell neoplasms in Girona, Spain: a population-based study, 1994–2020

Abstract Multiple myeloma is the most common malignant tumor originating in plasma cells. Its incidence varies across populations according to demographic and environmental factors, although its exact etiology remains unclear; reports on survival and advances in treatment are lac...

Circle of Willis-Guided Localization for Simultaneous Detection and Classification of Large Vessel Occlusions in Brain CTA

Abstract Large vessel occlusions (LVOs) are blockages in the brain’s major arteries that can cause severe neurological damage. Rapid and accurate detection using computed tomography angiography (CTA) is critical for timely stroke treatment. Here, we present a fully automated appr...

Genetic Testing After Heart Transplantation Uncovers Heritable Disease and Drives Family Screening

BACKGROUND: Genetic testing (GT) is established in ambulatory cardiomyopathy (CM), but its utility after heart transplantation (HTx) recipients remains poorly characterized. OBJECTIVES: This study aimed to evaluate the clinical utility of GT in adult HTx recipients with CM, focus...