Institut des Maladies Neurodégénératives

Rapid estimation of structural brain disconnection from binary lesion masks using DeepDisco

Abstract Mapping how focal brain lesions disrupt structural connectivity is key to understanding cognition, behavior, and neurological outcomes. However, traditional diffusion tractography pipelines are computationally intensive, require specialized data and expertise, and remain...

Generalizable and equitable automated ischaemic stroke lesion segmentation with vision transformers

Abstract Background Ischaemic stroke, a leading cause of death and disability, relies on neuroimaging for characterising the anatomical pattern of injury. Diffusion-weighted MRI (DWI) provides the most anatomically specific signal in acute ischaemic stroke but poses substantial c...