Institut de Recherche et d’Innovation

Improving pharmacokinetics and pharmacodynamics of berberine hydrochloride using solid dispersion: A therapeutic approach to hyperlipidemia

Berberine is an isoquinoline alkaloid that acts as a natural PCSK9 inhibitor. By inhibiting PCSK9, it upregulates Low-Density Lipoprotein (LDL) receptors and helps maintain lipid metabolism. Although it is a promising hypolipidemic agent, its clinical application is limited by po...

Gap-tuned exceptional skin effect in non-Hermitian flat bands

Flat-band states in Hermitian systems exhibit compact localization in the bulk due to geometric or symmetry constraints, while non-Hermitian skin effects drive state accumulation at boundaries via asymmetric lattice hoppings. Despite extensive efforts devoted to studying these tw...

Nanofibrous aerogels with continuous conductivity gradient for ultrabroadband absorption-dominant electromagnetic interference shielding

Electromagnetic interference (EMI) shields are limited by a severe impedance mismatch with free space, leading to strong reflections and secondary radiation. Here, we introduce ultralight all-polymer aerogels featuring a continuous through-thickness conductivity gradient (MCAs),...

Durable Interphase Engineering on SiO x Anodes Through Interfacial‐Enrichment‐Facilitated Polymerization

ABSTRACT Constructing a robust solid electrolyte interphase (SEI) is a proven strategy to enhance the performance of Si‐based anodes by accommodating severe volume swings and suppressing interfacial side reactions. However, existing strategies that rely solely on either chemical...

AssemblyMate: an interactive context-aware AI-XR co-worker with multimodal spatial-temporal reasoning for manufacturing assembly

In-situ assistance plays a vital role in enhancing operational performance and process reliability in manufacturing. Conventional operator training systems often rely on manual supervision from experienced workers, which can lead to inefficiency, inconsistent guidance, and high l...