Institut de Recherche en Sciences de la Santé

Optimizing HIV testing uptake among pregnant women in Burkina Faso: machine learning prediction and scenario-based intervention simulations using 2021 Demographic and Health Survey data

HIV testing uptake among pregnant women remains a public health priority in Burkina Faso. This study aimed to identify and rank key predictors of HIV testing uptake using machine learning (ML) approaches and to estimate potential gains under scenario-based intervention simulation...

Shared patterns of human milk composition link mammary gland function to infant growth

The mammary gland produces nutrient-rich human milk (HM), yet how mammary functional state shapes HM composition and infant outcomes remains poorly understood. We used HM multi-omics - metabolomics, proteomics, micronutrients, macronutrients, and HM oligosaccharides - across 1,54...

A remote sensing–based approach to the regionalization of socioeconomic indicators in an agricultural headwater catchment in Northern Benin

The agroecosystems of the rural continuum of the Sudano-Sahelian region of the Volta River Basin are undergoing severe degradation, resulting in serious declines in ecosystem service capacities and weakening community livelihoods, as agriculture remains the primary source of inco...

No geographical population structure of malaria vectors Anopheles gambiae and Anopheles coluzzii but weak structure in Anopheles arabiensis within Burkina Faso: implications for vector control and gene drive implementation

Abstract Background Malaria control tools are nowadays challenged by the expansion and persistence of insecticide resistance in the malaria vector along with the changes in vector behaviour. To complement and reinforce the existing control tools, innovative vector control methods...

Virological surveillance of chikungunya in Burkina Faso in 2024

Chikungunya is an emerging arbovirus disease transmitted by mosquitoes of the genus Aedes , mainly Aedes aegypti and Aedes albopictus . Since it was first identified in Tanzania in 1952, the virus has caused numerous epidemics around the world. Despite arbovirus surveillance sinc...

Participant attrition in a multi-regional population-based study in Africa: insights from the AWI-Gen study

Attrition in longitudinal studies, defined as the loss of participants over time, may threaten the validity of study results. This study examined patterns, magnitude, and risk factors for attrition in the AWI-Gen cohort. The study included 12,032 participants from six African sit...