Institut de Recerca Biomèdica Catalunya Sud

Targeting food addiction through an intensive energy-reduced Mediterranean diet lifestyle intervention: evidence from the 3-year PREDIMED-plus trial

Food addiction (FA) has been proposed as a behavioural phenotype linked to obesity, potentially influencing adherence and response to lifestyle interventions. Its role within long-term, multicomponent weight-loss programmes remains unclear. This study evaluated the impact of an i...

A feasibility pilot study of an AI-based emotional support application (TerapIA) in a Spanish-speaking community population: recruitment, retention and parameter estimation for a controlled trial

Before running a controlled trial of an emotional support application, it is worth checking that the trial can actually be run. We present a feasibility pilot study of TerapIA, the AI-based emotional support application of LenguajeNatural.AI, with a pre/post design and a control...

ADHD Symptoms in Parents of Children With or Without ADHD: Prospective Association With Children’s Quality of Life and Emotional and Conduct Problems (EPINED Cohort)

ADHD symptoms are frequently reported in parents of children with ADHD, however, their prevalence and association with children's mental health and quality of life (QoL) remain poorly understood. This study examines parental ADHD symptoms and their associations with children's me...

Generalization, Cross-ICU Transfer, and Explainability of a Mortality and Time-to-Discharge Framework for the Intensive Care Unit

Background: PADS combines two neural networks predicting ICU mortality and discharge within 48 h, placing critically ill patients into one of four clinically meaningful states. Developed on MIMIC-IV alone, it left open whether it generalizes to other ICUs, whether its models tran...

Myeloid-Derived Suppressor Cells (MDSCs) in Cardiovascular Risk of Obesity-Associated Diabetes

The dysregulation of immune homeostasis and the persistence of chronic, low-grade inflammation represent core pathophysiological drivers governing the onset and progression of metabolic and cardiovascular disorders. Myeloid-derived suppressor cells (MDSCs) comprise a highly heter...

Concurrent Assessment of Micro- and Nanoplastics and Bisphenol A in Non-Dialysis Chronic Kidney Patients and Hemodialysis Patients: Results from a Cross-Sectional Human Biomonitoring Study Focusing on Sex-Related Patterns

Patients with chronic kidney disease (CKD), particularly those receiving hemodialysis (HD), may be more vulnerable to exposure to micro- and nanoplastics (MNPs) and bisphenol A (BPA) because of impaired renal clearance and frequent contact to plastic-based medical devices. This s...

Eating Behavior Latent Profiles and Their Associations With Body Composition in Early Childhood: The CORALS Cohort

ABSTRACT Objective This study aimed to identify sex‐specific eating behavior profiles and assess the associations between eating behaviors subscales and profiles and body composition indices in Spanish preschoolers from the CORALS cohort. Methods We conducted a cross‐sectional an...

The first 72 hours of acute pancreatitis: patterns of variability in early clinical decision-making

To assess real-world adherence to evidence-based international guidelines in the early management of acute pancreatitis (AP), and to identify how variability in clinical decision-making is distributed during the first 72 h of care. This multicentre, cross-sectional survey was con...