Institut de Neurosciences des Systèmes

Data-driven mean-field within whole-brain models

Mean-field models provide a link between microscopic neuronal activity and macroscopic brain dynamics. Their derivation depends on simplifying assumptions, such as all-to-all connectivity, limiting their biological realism. Here, we introduce a data-driven framework in which a mu...

Hippocampal Seizure‐Related Burden is Associated with Accelerated Long‐Term Forgetting in Focal Epilepsy

Objective Memory impairment is a frequent comorbidity of focal epilepsy, incompletely explained by seizure frequency or structural pathology. Ictal and postictal hippocampal dysfunction disrupt memory processes, but their cumulative impact remains poorly quantified. This study in...