Institut de Cancérologie de l'Ouest

Descriptive Analysis of Epidemiology, Demographic Characteristics, and Survival of Dedifferentiated Liposarcoma in France

Dedifferentiated liposarcoma (DDLPS) is a rare soft tissue sarcoma with limited real-world epidemiologic data. This nationwide retrospective study describes the epidemiology, management, and outcomes of DDLPS in France using the NETSARC+ national sarcoma registry. A total of 1451...

An inertial‐based spiral device for separating rare tumor cells from liquid biopsies

Abstract Early detection of primary tumors and metastatic processes increases the success of anti‐tumor therapies and favors good prognoses. Within the current range of methods available to detect the presence of tumors, liquid biopsy is receiving particular attention as it is a...

Immunomodulatory Drugs and Cereblon E3 Ligase Modulators in Multiple Myeloma: 30 Years in the Making

Immunomodulatory drugs (IMiDs) have fundamentally reshaped multiple myeloma therapy, extending survival and establishing durable backbones across induction, relapse, and maintenance. Cereblon's identification as a druggable E3 ligase substrate receptor created the mechanistic pat...

Combined prognostic value of age at onset and socioeconomic status for long-term survival in metastatic breast cancer

We investigated the combined long-term prognostic value of age at onset and socioeconomic status (SES) on breast cancer overall survival (OS) and metastasis-free survival (MFS) in a cohort of women with metastatic breast cancer. Age at onset was defined as the age at primary diag...