Institut de Cancérologie de l'Ouest

Immunomodulatory Drugs and Cereblon E3 Ligase Modulators in Multiple Myeloma: 30 Years in the Making

Immunomodulatory drugs (IMiDs) have fundamentally reshaped multiple myeloma therapy, extending survival and establishing durable backbones across induction, relapse, and maintenance. Cereblon's identification as a druggable E3 ligase substrate receptor created the mechanistic pat...

Combined prognostic value of age at onset and socioeconomic status for long-term survival in metastatic breast cancer

We investigated the combined long-term prognostic value of age at onset and socioeconomic status (SES) on breast cancer overall survival (OS) and metastasis-free survival (MFS) in a cohort of women with metastatic breast cancer. Age at onset was defined as the age at primary diag...