Institution
Institut Català d'Oncologia
Recent research
- BiologyOpen access
Natural History of Rare Tumor Risk Syndromes: A Scoping Review to Inform Cost-Effectiveness Models
Background Hereditary cancer syndromes account for approximately 10% of all cancers. Many of these, classified as rare tumor risk syndromes (RTRS), lack comprehensive data on natural history, lifetime cancer risk, and the long-term impact of surveillance. These evidence gaps limi...
- Health & MedicineOpen access
Head and neck cancer (HNC) comprises a heterogeneous group of malignancies with substantial variation in incidence, risk factors, and outcomes across populations. Existing studies are often limited by regional scope or lack integration of epidemiological, clinical, and molecular...
- Society & EconomicsOpen access
Despite advances in cancer treatment, the growing global cancer burden underscores the need for comprehensive and supportive care to address the needs of patients and their families. However, access to psycho-oncological support remains often limited across healthcare systems. Th...
- BiologyOpen access
Abstract Epilepsy is characterized by the occurrence of at least two unprovoked seizures occurring more than 24 h apart, reflecting a predisposition to recurrent epileptic events. The role of dietary amino acids (AAs) in epilepsy is not clearly understood. To the best of our know...
- Health & MedicineOpen access
Background: Concurrent chemoradiotherapy (cCRT) followed by 1 year of consolidation durvalumab remains the standard of care for unresectable stage III non-small cell lung cancer (NSCLC), yet long-term survival is still limited and around 20% of patients present locoregional relap...
- BiologyOpen access
Oxaliplatin–fluoropyrimidine combinations are standard adjuvant therapy after radical resection of high-risk stage II and stage III colon cancer but expose many patients to toxicity while failing to prevent relapse in others. PEGASUS was a multicenter, single-arm, phase 2 trial e...
- Health & MedicineOpen access
Abstract Purpose We conducted the first multicentre Spanish real-world study assessing the efficacy and safety of stereotactic body radiotherapy (SBRT) in oligometastatic patients treated in routine clinical practice. Methods This retrospective, multicentre observational study in...
- Health & Medicine
Plain Language SummaryWhat is this summary about?This summary describes how well talquetamab worked and its safety at a median (midpoint) of 17–26 months follow-up from the MonumenTAL-1 study, which tested talquetamab treatment for a type of cancer called relapsed/refractory mult...
- BiologyOpen access
Ultraslow brain dynamics as neurophysiological markers of information sampling during learning
To learn, we must actively sample information from our environment: selecting, prioritizing, and extracting relevant cues. Here, we investigated whether ultraslow event-related potentials (ERPs) could track information sampling as participants learned new words from sentence cont...
- Health & MedicineOpen access
Abstract Hematopoietic cell transplantation, cellular and gene therapies, and (CAR)-T cells have revolutionized outcomes in hematologic disorders. However, major disparities persist in their availability, accessibility, and affordability, particularly in low- and middle-income co...
- Health & MedicineOpen access
Tobacco use remains disproportionately high among people receiving treatment for alcohol or cannabis use, yet it is rarely addressed in substance use services. This study explored the lived experiences of people who smoke while undergoing treatment for alcohol and/or cannabis use...
- Health & MedicineOpen access
Treatment-free remission (TFR) is an established therapeutic goal for patients with chronic myeloid leukemia (CML) achieving sustained deep molecular response (DMR) on tyrosine kinase inhibitors (TKIs). However, evidence on TFR following bosutinib discontinuation remains limited....