Innovation Team (China)

Antidepressant Effects of Lactoferrin-Modified Sodium Alginate-Based Saikosaponin A Nanogels via Intranasal Administration: Involvement of Olfactomedin-Family Proteins

Objective: To develop a lactoferrin-modified sodium alginate nanogel loaded with saikosaponin A (SA-Lf-NG@SAA) and evaluate its potential antidepressant-like effects following intranasal administration. Methods: SA-Lf-NG@SAA nanogels were prepared and optimized using single-facto...

Preparation of Salt‐Resistant Gemini Surfactants via Ethylene Oxide Group Regulation for Enhanced Oil Recovery

ABSTRACT Conventional anionic surfactants generally exhibit poor salt tolerance and reduced interfacial activity under high‐salinity reservoir conditions, limiting their application in enhanced oil recovery (EOR). To address this issue, a series of anionic–nonionic isotridecanol...

Oral Edible Zein/CitricAcid Nanocomposite EnablesIntestinal Delivery of Resveratrol for Effective Ulcerative ColitisTherapy

Abstract Resveratrol (Res) is a plant polyphenol with diverse bioactivities, yet its application is limited by poor water solubility and low bioavailability. Therefore, an edible nanodelivery system composed of a zein/citric acid complex was developed to encapsulate Res@ZC-NPs sh...