Inje University Haeundae Paik Hospital

Thermal Quantitative Sensory Testing in Zoster-related Pain

OBJECTIVES: Thermal detection abnormalities in herpes zoster (HZ) and postherpetic neuralgia (PHN) remain incompletely characterized. We compared pathologic-site cold and warm detection threshold abnormalities between HZ and PHN, assessed within-patient asymmetry between patholog...

A Retrospective Multicenter Study of Measles Seropositivity in Korea from 2014 to 2024

Background: Measles is a highly contagious viral disease requiring high herd immunity.Although the Republic of Korea has maintained measles elimination through national immunization programs, sporadic cases continue to occur.We evaluated age-and period-specific measles immunity l...

Fasting Duration and Differences Across Routine Laboratory Tests

Importance Fasting before blood collection is widely practiced to reduce preanalytical variability, yet whether fasting-related differences are clinically meaningful across a broad panel of routine analytes has not been systematically evaluated using clinical data. Objective To e...

Nationwide Multicenter Laboratory-Based Analysis of Varicella-Zoster Virus IgG and IgM Seropositivity in Korea, 2014–2024

Background: Varicella-zoster virus (VZV) remains an endemic, vaccine-preventable infection in Korea, despite high national vaccination coverage. Understanding long-term population immunity trends is essential for refining the disease-control and immunization policies. In this nat...

Trastuzumab plus nivolumab with gemcitabine and cisplatin as first-line therapy for HER2-positive unresectable biliary tract cancer: a phase 1b/2 trial

Biliary tract cancers (BTCs) are associated with poor outcomes despite recent incorporation of immune checkpoint inhibitors into first-line chemotherapy. Human epidermal growth factor receptor 2 (HER2) overexpression or amplification defines a therapeutically targetable subset of...

Prognostic Role of Adverse Events in a Worldwide Population of Patients with Biliary Tract Cancer Treated with Chemo-Immunotherapy

Background: Biliary tract cancers (BTCs) are aggressive malignancies with limited treatment options. The addition of durvalumab or pembrolizumab to cisplatin–gemcitabine improves overall survival (OS), but validated biomarkers of benefit remain limited. Immune-mediated adverse ev...

Short-Term Efficacy of Tegoprazan Compared With Esomeprazole in Patients With Non-Erosive Reflux Disease and Nocturnal Heartburn Symptoms: A Double-Blind, Randomized Controlled Trial

Objectives: Tegoprazan is a novel potassium-competitive acid blocker that rapidly suppresses acid secretion. This study aimed to evaluate the efficacy of tegoprazan 50 mg compared with esomeprazole 20 mg in patients with non-erosive reflux disease and nocturnal heartburn symptoms...

Predictors of Early Versus Late Atrial Tachyarrhythmia Recurrence After Cryoballoon Ablation by Atrial Fibrillation Type

ABSTRACT Introduction Patient characteristics and predictors of early (ERAT) and late (LRAT) recurrence of atrial tachyarrhythmia by atrial fibrillation (AF) type after cryoballoon ablation (CBA) remain poorly defined. Methods Using the Korean Heart Rhythm Cryoballoon Registry (1...

Single-port robotic areolar thyroidectomy: technical feasibility and clinical outcomes of 64 consecutive cases

Abstract Background Single-port robotic areolar (SPRA) thyroidectomy is a recent refinement of the bilateral axillo-breast approach (BABA) that employs the da Vinci single-port system to establish a single-trajectory corridor while preserving a scarless neck. However, clinical da...

Early On-Treatment Host Fitness Dynamics Refine Prognostic Stratification in Advanced NSCLC Receiving First-Line Immunotherapy

PurposeWe assessed whether baseline and early on-treatment measurements of host fitness using the Prognostic Nutritional Index (PNI) provide complementary prognostic information in advanced non-small cell lung cancer (NSCLC). Materials and MethodsWithin the prospective, multicent...

Psychedelic-informed Therapeutics and Functional Decoupling: Toward Experience-independent Rapid-acting Antidepressants

Major depressive disorder remains a leading cause of global disability, and many patients show limited response to conventional antidepressants.Increasing evidence suggests that a substantial subgroup exhibits chronic low-grade inflammation, which may constrain synaptic plasticit...