Infectious Diseases Research Collaboration

Temporal organization of the Plasmodium falciparum transcriptome prioritises genetic polymorphisms associated with artemisinin response

Abstract Artemisinin-based combination therapies (ACTs) have substantially reduced the global burden of malaria, but the emergence and spread of artemisinin partial resistance (ART-R) threatens these gains. Although mutations in Plasmodium falciparum kelch13 (pfk13) are establish...

Health services intervention integrating HTN and HIV care improves long-term blood pressure control among people living with HIV in Uganda

Background Globally, the prevalence of hypertension (HTN) among people with HIV (PWH) has increased dramatically over the last decade. In a cluster randomized trial, we evaluated the effect of a multicomponent intervention model on blood pressure (BP) control among PWH in rural U...

Uptake of R21/Matrix-M malaria vaccine and associated factors among children eligible for vaccination in Kole and Kwania districts, Northern Uganda: a cross-sectional study

The introduction of R21/Matrix-M (R21) vaccine as a malaria control strategy provides an opportunity to reduce the disease burden. However, there is limited evidence on its uptake and what affects the uptake, information that is important for the successful implementation of the...

Participant perspectives on a person-centred care model for mobile individuals in HIV care from the SEARCH Dynamic Choice Treatment trial in rural Kenya and Uganda

Introduction Mobile populations experience difficulties maintaining antiretroviral therapy (ART) adherence and HIV care engagement. We sought to explore participant perceptions of a patient-centred model aimed at enhancing care engagement through ‘dynamic choice’ treatment servic...