Indian Institute of Science Education and Research Mohali

Polyethylene Glycol Crowding Enhances Protease-Mediated Albuminolysis with Distinct Surface Tension Dynamics

Abstract Macromolecular crowding profoundly influences biomolecular interactions and enzymatic processes through excluded volume effects, providing opportunities to optimize enzymatic reactions for diverse applications. To this end, albuminolysis is particularly important for var...

Towards an operational seasonal forecasting system for the Arabian Peninsula

Seasonal forecasting is a key tool for managing climate risks in arid regions, yet its performance over the Arabian Peninsula (AP) remains insufficiently characterized. In this study, we developed and evaluated a multi-model seasonal forecasting system for the AP, comparing simul...

A geometric decomposition of the Coulomb integral for uniform planar objects

We present a vector-calculus derivation of the electrostatic potential of uniformly charged planar objects: the circular disk, the arbitrary triangular plate, the rectangular plate and the regular polygon. By geometrically decomposing the Coulomb integral, the potential is expres...

Lewis Acid Integrated Bifunctional Covalent Organic Framework for Photocatalytic Regioselective C3-Carbonylation of Indoles

Abstract The regioselective carbonylation of indoles have attracted significant recent attention owing to the ubiquitous presence of indole derivatives in pharmaceuticals and natural products. Aldehydes are very appealing as effective carbonylation sources; however, methods to ac...

Beyond rare gases: Cooling of trapped BN− ions by H2 molecules

Quantum dynamics of collisional cooling of the BN- anion in a cold trap is carried out by using the ortho- and para-H2 molecules as a buffer gas. The calculations are performed using the full four-dimensional interaction potential energy surface in which both BN- and H2 are treat...

TRIM62 facilitates influenza A virus entry by regulating WASH-dependent endosomal trafficking

Abstract Endocytosis enables efficient cargo uptake while restricting uncontrolled cellular entry, yet how this balance is enforced during endocytic uptake remains poorly understood. Using influenza A virus (IAV) as a model cargo, we reveal a previously unrecognized role for the...

Metal–Organic Frameworks for Dinitrogen Reduction to Ammonia: Active-Site Engineering, Mechanistic Pathways, and Reliability Challenges

Abstract Metal–organic frameworks (MOFs) provide a highly tunable platform for artificial dinitrogen reduction to ammonia because metal nodes, organic linkers, defects, pore environments, and interfaces can be engineered at molecular and atomic levels. This review critically exam...

Pd-Catalyzed Chemodivergent Monodefluorinative Cascade Cyclizations of gem -Difluorovinyl-Conjugated Alkynylanilines to Fluorinated Benzocarbazoles and Indoloisoquinolines

Abstract An efficient one-pot Pd-catalyzed reaction medium-directed chemodivergent protocol has been developed that enables the controlled assembly of meta-fluorinated benzocarbazoles, fluoroindoloisoquinolines, and their halogenated analogues from easily synthesizable gem-difluo...

Phosphine‐Free NNN Bis‐Iminopyridine Supported Zinc(II) Catalysts: A Sustainable Platform for C─C Bond Formation Reactions via Borrowing Hydrogen Approach of Primary Alcohols

ABSTRACT In this study, we present a methodology for direct C─C bond formation using renewable primary alcohols as alkylating agents, catalyzed by base metal‐derived Zn(II) complexes. We utilized two well‐defined phosphine‐free NNN bis‐iminopyridine pincer ligands (L1 and L2) for...

Microbiota of Polistine Wasps: A Comparison of Four Species From India

Studying the microbiota of closely related species can provide important insights into the essential roles of symbiotic microbes in the physiology of organisms. We have studied the bacterial microbiota of four polistine species (Vespidae: Polistinae), from India, using 16S rRNA a...

Optimization of cooling power of a thermoelectric refrigerator: a unified approach

Abstract We analyze the steady-state formalism for optimizing the cooling power of a thermoelectric refrigerator (TER), unifying the endoreversible and exoreversible approximations within one framework. Although the cooling power is non-optimizable within the endoreversible model...

Hybridizing MXenes with MOFs: a pathway to smart sensing platforms and efficient water remediation

The need for the efficient platforms creating innovative applications in the field of sensing, wastewater treatment, and industrial safety has resulted in the development of novel and advanced hybrid materials with unique morphological structures and superior performance. Hybrid...

Sequence‐encoded determinants drive distinct early aggregation pathways and different structural outcomes in PNT1 fibrils across Henipavirus members

Protein aggregation is increasingly recognized as a biologically relevant process in viral proteins, yet the molecular determinants governing such phenomena remain poorly understood. Intrinsically disordered proteins (IDPs) are ubiquitous in viral proteomes, where conformational...

Growth mechanisms and characteristics of near-interface traps in SiC/SiO2 interfaces for next generation power devices: A short review

Silicon carbide (SiC) has emerged as a leading wide-bandgap semiconductor for high-voltage and high-temperature power electronics; however, the performance of SiC metal–oxide–semiconductor (MOS) devices remain limited by the electrical quality of the SiC/SiO 2 interface. This rev...