Institution
Indian Institute of Science Education and Research Kolkata
Recent research
- Engineering & Technology
Abstract Organic π-conjugated chromophores with tunable electronic structures are promising candidates for nonlinear optical (NLO) and optical limiting (OL) applications. Herein, we report a series of arylhydrazono-1,3-diketones incorporating pyrrole, N-methylpyrrole, thiophene,...
- Materials & Energy
Abstract Triple-negative breast cancer (TNBC) remains difficult to treat because of limited molecular targets and multidrug resistance. Here, we develop CPB, a biodegradable poly(ε-caprolactone)-polymeric prodrug nanoplatform integrating biotin-mediated uptake, triphenylphosphoni...
The dimethyldihydropyrene photochromic system is a 14π-electronic framework that switches to a less-aromatic, nonplanar system under visible light. In this work, we unravel a neutral phosphorus heteroatom-appended dimethyldihydropyrene (DHP) photoswitchable system that acts as a...
- Materials & Energy
Electrochemical Synthesis of Spirodienones with Sequential Ring Expansion to Fused 6–7–6 Tricycles
Abstract An intramolecular electro-oxidative spirocyclization of tethered arenes is developed to access spirodienones under metal- and chemical-oxidant-free conditions. This method exhibits good functional group tolerance, allowing a broad spectrum of substrates with yields of up...
- BiologyOpen access
Abstract Biofilm represents a complex aggregation of bacteria embedded within a self-produced extracellular polymeric substance (EPS). We investigated the characteristics of mycobacterial biofilm using Mycobacterium smegmatis (Msm) as a model organism. By combining transcriptomic...
- Materials & EnergyOpen access
Intrinsic Electric Field Driven High Sensitive Photodetection in Alloy TMDC MoSSe
ABSTRACT Alloying offers an effective way to improve the functionality of transition metal dichalcogenides (TMDCs) in both fundamental research and optoelectronic applications, as it allows for engineering their electronic and optical properties. This study investigates the optoe...
- BiologyOpen access
Abstract Vitamin B12 (cobalamin) is an evolutionarily optimized Co-corrin redox cofactor capable of accessing low-valent cobalt states to mediate challenging biological transformations. Here, we reengineer this biological redox platform into an electrode-addressable catalyst for...
- Materials & Energy
ABSTRACT Achieving multicolor ultralong room‐temperature phosphorescence (URTP) from a metal‐free single benzenic framework represents a fundamental challenge owing to inefficient intersystem crossing. Herein, we demonstrate a precursor engineering strategy that enables excited‐s...
- Materials & Energy
The Rise of Gallol Chemistry in Polymer Science: Design Principles and Multifunctional Applications
Abstract Gallol pendant polymers have become a highly adaptable class of bioinspired materials with significant potential in biomedical applications and other advanced functional materials by translating the multifunctionality of naturally occurring polyphenols into synthetic pol...
- Materials & Energy
Abstract We report here (bio)polymer-template-induced generation of room-temperature phosphorescence (RTP) in trimeric halogenated phenylpyridinium derivatives in aqueous media and in the film state. For this purpose, two different types of anionic templates were introduced: hepa...
- Materials & EnergyOpen access
Transformative Materials Research: Defining Conceptual Change across Scales
Abstract What qualifies as transformative materials research? In this Viewpoint, we use “transformative” to denote work that forces revision of underlying assumptions, enables generalization across systems, or reveals regimes inaccessible to existing frameworks. The term is widel...
- Health & MedicineOpen access
Intra-cluster receptor density (IRD): A molecular switch for TNFR1 clusters’ signaling
Abstract Tumor Necrosis Factor Receptor 1 (TNFR1) signaling regulates cell fate in inflammation, immune responses, and tumorigenesis. While TNF-α–mediated TNFR1 pathways are well known, the role of receptor clustering remains unclear. Utilizing homo-FRET using fluorescence anisot...
- Climate & EnvironmentOpen access
Abstract Hydrous oxyhydroxides such as FeOOH and AlOOH have been proposed as potential carriers of hydrogen into Earth's deep mantle. However, these phases form extensive solid solutions in natural systems, and the influence of Al incorporation on the stability and elastic proper...
- AI & ComputingOpen access
AILQA: Evaluating AI-driven legal question answering systems for the indian legal system
Abstract This comprehensive study introduces an advanced A rtificial Intelligence for I ndian L egal Q uestion A nswering or system tailored for the Indian legal context. leverages a variety of embedding and generative models, including the latest Large Language Models (LLMs), to...
- Engineering & Technology
Abstract Transition-metal halides are of particular interest because their partially filled d-orbitals, containing unpaired electrons, give rise to distinctive magnetic and electronic properties. Notably, hydration can act as a structural switch, inducing substantial modification...
- Materials & Energy
Abstract Two-phase-engineered bimetallic alloys with tunable crystallographic defects offer a promising platform for proton-coupled electron-transfer in electrocatalytic nitrate reduction (NO3RR) to ammonia, providing a sustainable alternative to the Haber–Bosch process. Alloying...