Indian Council of Medical Research

Treatment and tracking algorithm for iron deficiency anaemia among children and adolescents— a policy informed evidence— based framework for India

Background and objectives The Anaemia Mukt Bharat (AMB) programme advocates for ‘test, treat and track’ strategy. However, limited coverage, poor adherence, workforce shortages and inconsistent follow up, affect implementation. Recent programme monitoring data indicate suboptimal...

Bridging the Gaps: Research Priorities and Policy Directions for Tribal Health in Odisha

Abstract Background: Building on the tribe-specific epidemiological data provided by the Odisha Tribal Family Health Survey (OTFHS), the present study employed a priority-setting approach to identify health challenges, research priorities, and actionable strategies for tribal hea...

Pulmonary Function Impairment From Occupational Particulate Exposure Among Informal Sector Workers in South Asia: A Systematic Review and Meta‐Analysis

ABSTRACT Background Tens of millions of workers in South Asian informal industries are exposed daily to hazardous dusts and fumes without regulatory protection. Despite the scale of this workforce, no quantitative synthesis of spirometric and symptomatic evidence from this popula...

Comparative pathogenicity study of monkeypox virus Clade Ib and Clade IIb in a rabbit model

Manuscript data for review

Sentinel serosurvey for Mpox virus infection among key populations in India: Evidence of sporadic past exposure beyond travel-related cases

Background and objectives Mpox, declared a public health emergency of international concern by WHO, has demonstrated sporadic transmission globally. While India reported 66 confirmed cases predominantly linked to international travel, the possibility of silent community circulati...

Prevalence and Determinants of Never Treatment During Mass Drug Administration for Lymphatic Filariasis: A Systematic Review and Meta-Analysis

Objectives: The term “never treated” refers to individuals who self-report having never ingested tablets during any round of Mass Drug Administration (MDA) against Lymphatic Filariasis (LF). This study estimated the pooled prevalence of never-treated individuals with MDA for LF a...

Occupational stress and psychological distress among railway loco pilots in Bengaluru, India: A mixed-methods study

Abstract Objective Occupational stress and mental health conditions are increasingly prevalent among transport workers, especially railway loco pilots operating under prolonged, irregular, and high-pressure schedules. Methods This mixed-methods study assessed work-related stress...

Genome-wide association analysis of endometriosis in Indian women supports shared genetic susceptibility and suggestive population specific signals

Endometriosis is an estrogen-dependent, chronic gynaecological disorder affecting approximately 10% of women of reproductive age and is associated with pelvic pain, infertility, and reduced quality of life. Genetic studies indicate substantial heritability, yet genome-wide associ...

Pan genome clustering identifies a novel mosaic prophage specific to Salmonella Enteritidis lineage associated with the invasive disease in India

Abstract Salmonella enterica serovar Enteritidis is a leading cause of bloodstream infections (BSIs), particularly in sub-Saharan Africa (sSA). While typhoidal salmonellosis is well documented in South Asia, the burden and genomic characteristics of non-typhoidal Salmonella (NTS)...

Community Street Play Versus Facility-based Screening for Mental Health Literacy in Rural India: A Mixed-methods Quasi-experimental Study

Background: Community-based approaches to mental health literacy (MHL), including street theatre, remain underrepresented. No study has compared street play with primary care facility-based screening as parallel MHL strategies. This study evaluated the effectiveness and acceptabi...

Analysis of measles outbreaks reported to Integrated Disease Surveillance Programme (IDSP), India, 2019–2023

<title>Abstract</title> <bold>Background:</bold> In 2022, an estimated 1,36,000 measles deaths were reported worldwide, mostly in children under five. In 2022, thirty-seven countries reported extensive or disruptive measles outbreaks by the WHO, while only 22 countries reported s...

Electrohydrodynamically microencapsulated, lyophilized, and fermented probiotics outperform in-feed antibiotics in promoting growth performance and gut health of Bos indicus calves

Probiotics are increasingly explored as an alternative to antibiotics for improving calf health, however, their efficacy can be affected by the method of delivery and survival of viable cells within the gastrointestinal tract. Comparative studies evaluating different probiotic de...

Genomic and molecular insights into AMR, virulence, and toxin of Shiga toxin–producing Escherichia coli isolated from local curd foodborne outbreak in Manipur

This study reports the isolation, characterization, and genome analysis of Escherichia coli isolated from curd, revealing potential pathogenic and multidrug-resistant characteristics.15 individuals who consumed the suspected contaminated local curd developed symptoms included acu...

Pilot validation of a piezo‑resistive gnathodynamometer for maximum voluntary bite force measurement in adults: a cross sectional comparative study

Maximum voluntary bite force (MVBF) is a key indicator of masticatory system function, influenced by cranio-mandibular biomechanics, neuromuscular coordination, and dental status. Conventional bite force devices, though widely used, are limited by their bulk and potential discomf...

Antibiotic development and a path to access in India

Antibiotic development has historically been concentrated in high-income countries. We discuss how India is emerging as an important centre for antimicrobial development, and the implications for global health and equity of access to life-saving therapies. India is emerging as an...