Institution
Independent University of Moscow
Recent research
- Health & MedicineOpen access
The clinical response to elexacaftor/tezacaftor/ivacaftor (ETI) in people with cystic fibrosis carrying the rare cystic fibrosis transmembrane conductance regulator (CFTR) variant W1282R has not been well characterized. We retrospectively analyzed 12 people with cystic fibrosis t...
- BiologyOpen access
Spiking simulations of the Drosophila connectome routinely assign each synapse an excitatory or inhibitory sign by mapping the neurotransmitter (NT) predicted for the presynaptic body to a polarity. Using the recently released MaleCNS v1.0 whole-central-nervous-system connectome...
- BiologyOpen access
Spiking simulations of the Drosophila connectome routinely assign each synapse an excitatory or inhibitory sign by mapping the neurotransmitter (NT) predicted for the presynaptic body to a polarity. Using the recently released MaleCNS v1.0 whole-central-nervous-system connectome...
- AI & ComputingOpen access
Near-derivations And Their Applications to Lie Algebras
Abstract E.B. Vinberg’s concept of quasi-derivations of algebras is extended to a broader framework of near-derivations . This deepens connections between Poisson geometry and Lie theory. Although basic results apply to arbitrary algebras, our substantial applications concern the...
- Physics & SpaceOpen access
This paper introduces the Principle of Maximal Consciousness (PMC), a theoretical framework addressing the observer typicality problem in anthropic cosmology. Its central mechanism, the Principle of Proportional Indication (PPI), assigns observer weight according to the total mea...
- BiologyOpen access
Soil health assessment using buried cotton underpants with the help of 1000 citizen scientists
Societal Impact Statement Soil is a vital resource for life on Earth. Although many soils are degraded, societal awareness of soil‐related issues is limited. To highlight soil as a key resource and fascinating study system, we initiated a citizen science project together with 100...
- Physics & SpaceOpen access
This paper introduces the Principle of Maximal Consciousness (PMC), a theoretical framework addressing the observer typicality problem in anthropic cosmology. Its central mechanism, the Principle of Proportional Indication (PPI), assigns observer weight according to the total mea...
- Society & EconomicsOpen access
Which QTT numbers are pure, anchored, keystone-dependent, or structural? The Keystone Audit classifies every headline result before judging its numerical landing. Its paper-native master split remains \[ \boxed{ \mathcal R = \mathcal R_{\rm U}\sqcup \mathcal R_{\rm A}\sqcup \math...
- AI & ComputingOpen access
Imagine to Ensure Safety in Hierarchical Reinforcement Learning
This work investigates the safe exploration problem in reinforcement learning, where an agent must maximize cumulative performance while simultaneously satisfying safety constraints. This challenge becomes particularly difficult in long-horizon tasks because safe reinforcement le...
- Society & EconomicsOpen access
A research repository by Iskhak Hamzatovich Isaev presenting a comprehensive program applying Random Matrix Theory (RMT) to the analysis of large language models (LLMs). Thread 1 — Spectral statistics of LLM activations. Covariance matrices of GPT-2 hidden-state activations exhib...
- Society & EconomicsOpen access
A research repository by Iskhak Hamzatovich Isaev presenting a comprehensive program applying Random Matrix Theory (RMT) to the analysis of large language models (LLMs). Thread 1 — Spectral statistics of LLM activations. Covariance matrices of GPT-2 hidden-state activations exhib...