Immune Regulation (United Kingdom)

HLA class I expression and tumor immune infiltration together shape colon cancer immune contexture

Background The relative contribution of HLA class I molecules—including classical HLA class Ia (HLA-A, -B, -C) and non-classical HLA class Ib (HLA-E, -F, -G)—to shaping the tumor immune microenvironment in colon cancer remains insufficiently defined. We investigated how their exp...