IMDEA Food

Hypothyroidism Improves Survival in Experimental Peritonitis

Abstract Hypothyroidism decreases the basal metabolic rate. Using three models of peritonitis, intraperitoneal LPS plus Zymosan challenge, cecal slurry-induced intraperitoneal infection, and cecal ligation and puncture, we demonstrate that hypothyroid mice show enhanced survival...

Baseline Ferritin and Body Composition as Correlates of Longitudinal Metabolic Changes During an Energy-Restricted Mediterranean-Style Intervention Across Three Overweight Phlogistic-Related Clinical Conditions

Background/Objectives: Chronic inflammation accompanies obesity, but correlations of longitudinal changes during dietary follow-up remain unclear. We described inflammatory profiles and examined associations of baseline ferritin and body composition with changes during a 32-week...

Epigenetic changes reveal that vitamin B12 intake is associated with lower insulin resistance in older adults

Abstract Background Dietary choices influence both risk and development of type 2 diabetes (T2D), but the precise mechanisms remain incompletely described. Dietary intake and lifestyle behaviors can alter epigenetic states with subsequent modulations on gene expression which then...