Imam Hossein University

Targeting ferroptosis in cancer: molecular mechanisms and emerging therapeutic strategies

Ferroptosis, an iron-dependent form of regulated cell death characterized by the lethal accumulation of lipid peroxides, has emerged as a pivotal pathway in cancer biology and a promising therapeutic target. This review synthesizes the core molecular machinery governing ferroptos...

Anti-biofilm and quorum sensing-modulatory effects of quercetin-functionalized Capparis spinosa fruit-derived silver nanoparticles against multidrug-resistant Pseudomonas aeruginosa

Abstract Biofilm formation and quorum sensing (QS) systems are key determinants of pathogenicity and therapeutic resistance in multidrug-resistant (MDR) Pseudomonas aeruginosa , making these pathways attractive targets for combating chronic biofilm-associated infections. In this...