Imaging, Brain, and Neuropsychiatry

Exploring the Modalities of Combining Biological Models

Abstract This article examines how biological models are combined in biomedical research. It analyzes the notion of epistemological space, understood not as an abstract space of epistemic possibilities but as a framework for coordinating heterogeneous models through zones of part...

Assessing glymphatic role in the association between choroid plexus enlargement and white matter lesions load: The uncertain path through diffusion tensor imaging along the perivascular space (DTI-ALPS)

Background The choroid plexus (CP) is involved in cerebrospinal fluid production, immune surveillance, and brain fluid homeostasis. CP enlargement has been linked to neuroinflammation, glymphatic dysfunction, and white matter lesion (WML) burden, but the mechanisms underlying the...

20 Updates on Magnetic Resonance Imaging assessment of tumour MicrOStructure in GlioblastomA: A cross-sectional study (The MIMOSA Study)

Abstract The MIMOSA (Magnetic Resonance Imaging assessment of tumour MicrOStructure in GlioblastomA) study is recruiting patients with a presumed diagnosis of glioblastoma (GBM) pre-operatively to receive advanced diffusion-weighted magnetic-resonance-imaging (DW-MRI) using the C...

FOCUS: a feature optimization and cascaded unified screening strategy for computer-aided pathology-based glioma molecular subtype classification

Abstract Background Accurate classification of Isocitrate Dehydrogenase (IDH) mutation status is crucial for the diagnosis and treatment of adult-type diffuse gliomas as defined by the 2021 World Health Organization (WHO) Classification. However, conventional histological and mol...