Ikerbasque

Surface-Functionalized Nanofibers via Green Electrospinning: A Sustainable Platform for Enzyme Immobilization

Abstract In this work, we present a sustainable and efficient approach for the fabrication of surface-functionalized nanofibers via green electrospinning, an aqueous-based technique that employs polymer latexes and eliminates the need for organic solvents. Three carboxylic acid a...

Electron spin resonance in scanning probe microscopy: From single‐spin spectroscopy to atomically engineered quantum operations

Abstract Electron spin resonance (ESR) is one of the most powerful spectroscopic methods for probing systems with unpaired electronic spins. Conventional ESR has usually relied on the detection of large spin ensembles, thereby averaging over local environments and suppressing mic...

In Situ Analysis of Chiral Gold Nanorod Growth by Nanofluidic Liquid-Phase Electron Microscopy

Abstract Chiral gold nanoparticles exhibit unique chiroptical properties, but their integration into plasmonic devices requires an understanding of the formation of chiral features and controlling their growth on substrates. Here, we combine microfluidic synthesis and liquid-phas...

DNA methylation differences between female and male X chromosomes in human brain

Abstract Background DNA methylation is a key epigenetic mechanism of sex chromosome regulation. However, DNA methylation studies often exclude X chromosomes. Moreover, widely used DNA methylation assays interrogate biased subsets of CpGs, rather than assessing CpGs across the who...

Design and analysis of smooth geometry‐conforming lattices via Generalized Bézier patches

Abstract We propose a novel methodology to model globally G 1 geometry‐conforming metamaterials using Generalized Bézier‐based (GB) patches. Since every canonical tile is inscribed in a unit cube, we exploit its natural decomposition in octants and design multi‐sided patches for...

Rethinking glyme electrolytes in sodium batteries: from passive solvents to active reaction media

Sodium-based batteries are emerging as promising alternatives to lithium technologies owing to the abundance and low cost of sodium. However, their performance is strongly governed by electrolyte chemistry. This perspective examines the role of glyme-based electrolytes in sodium...

Geometry-enforced topological chiral fermions in amorphous chiral metals

Since the prediction and observation of topological Weyl semimetals (chiral TSMs), there have been enormous efforts to characterize further condensed matter realizations of chiral fermions. These efforts were dramatically accelerated by the subsequent discovery of a profound link...

From Platform Development to Scale-Up: Stable Producer Cell Line-Based Lentiviral Vector Manufacturing

Background: The development of stable producer cell lines (SCLs) represents a promising alternative for lentiviral vector (LVV) manufacturing, offering improved reproducibility and reduced manufacturing costs. In previous work, our group established an SCL generation platform bas...

From printing to intelligence: Smart polymer composite actuators for next-generation soft robotics

Smart polymer composite actuators are emerging as enabling materials for next-generation soft robotics by combining mechanical compliance, multifunctionality, and programmable responsiveness within lightweight architectures. Their ability to convert electrical, thermal, magnetic,...

Order Parameter Discovery for Quantum Many-Body Systems

Quantum phase transitions reveal deep insights into the behavior of many-body quantum systems, but identifying these transitions without prior knowledge of order parameters remains a significant challenge. In this work, we introduce a method for constructing phase diagrams using...

Two-dimensional topological quantum chemistry and catalog of topological materials

Two-dimensional (2D) topological materials host symmetry-protected, disorder-robust edge states central to quantum technologies. Yet they remain scarce compared with their 3D counterparts. We adapted the topological quantum chemistry formalism to layer groups and studied the band...

2D theoretically twistable material database

The study of twisted two-dimensional (2D) materials, in which twisting layers create moiré superlattices, has created opportunities for investigating topological phases and strongly correlated physics. The broader potential of a seemingly infinite set of twistable 2D materials re...

Benchmarking control strategies for wave energy converters: From idealised knowledge to realistic operation

Maximising energy extraction in wave energy converters remains challenging due to the non-causal nature of the optimal control, complex interactions and real-time constraints. This paper presents a benchmarking of four strategies: LiTe-Con, LiTe-Con+, model predictive control (MP...

Carbon Dioxide Derived Polycarbonate Nanocomposites With Multiwalled Carbon Nanotubes: Conductive and Piezoresistive Materials Towards Sustainable Electronics

ABSTRACT Bisphenol A polycarbonates are widely employed material among others, in electronics but their synthesis entails healthy concerns. Polycarbonates (PCs), thanks to their carbonate moiety, are the ideal candidates to substitute fossil feedstock by carbon dioxide (CO 2 ) in...

Supramolecular Biopolymer/Prussian Blue Hydrogels as Injectable Semisolid Electrodes for Shape-Conformable Electrochemical Energy Storage Devices

Abstract The transition toward electrified transport, renewable energy integration, and wearable electronics demands sustainable, deformable energy storage systems capable of conforming to complex geometries while maintaining mechanical and electrochemical functionality at ambien...

Hippocampal contributions to reading processes

Abstract The cortical substrates of typical reading have been extensively investigated. However, the functional contributions of subcortical regions to reading remain poorly understood and are largely absent from current neuroanatomical models. In the present fMRI study, we analy...

B7-H6 orchestrates oncogenic signaling and represents a therapeutic vulnerability in metastatic clear cell renal cell carcinoma

B7-H6 (NCR3LG1) is an immune checkpoint protein belonging to the B7 family of immunomodulatory proteins and serves as a ligand for the natural cytotoxicity triggering receptor NKp30 (NCR3) expressed on natural killer (NK) cells. In addition to its extracellular immunomodulatory d...

Noncarbohydrate Inhibitors of Sialic Acid-Binding Immunomodulatory-Type Lectin-7 (Siglec-7) Discovered from Genetically Encoded Bicyclic Peptide Libraries

ABSTRACT Glycan-binding proteins (GBP) are among the most difficult to drug targets. This deficiency delays clinical progress for therapeutically important GBPs. We employed bicyclic genetically encoded libraries (BiGELs), produced by chemical modification of phage-displayed libr...

Radon-induced backgrounds in the NEXT-100 experiment

A bstract The NEXT-100 detector at the LSC aims at the first competitive search for the 0 νββ decay using a high-pressure 136 Xe electroluminescent time projection chamber. The first low-background run of NEXT-100 at 3.95 bar has been devoted to the measurement of the radon-induc...

A cluster-randomized controlled trial of a family-based psychosocial intervention to prevent childhood obesity from preschool ages: the PRESAFALIN study protocol

Abstract Background: Childhood obesity is a major global concern, and Spain's high obesity rates highlight the urgent need for effective and innovative interventions in early age. The PRESAFALIN study aims to promote parental competence, self-efficacy, and resilience to improve c...