Hunan Children's Hospital

Clcn6 mRNA and ClC-6 protein expression in mouse central nervous system

To investigate the expression patterns of Clcn6 mRNA and ClC-6 protein in postnatal mouse of distinct region of central nervous system (CNS) and developmental stages. Distinct CNS regions, including cerebral cortex, hippocampus, cerebellum, brainstem, olfactory bulb, hypothalamus...

Subcutaneous Belimumab Demonstrates Consistent Steady-State Pharmacokinetics and is Well Tolerated in Paediatric Patients with SLE in China: An Open-Label Study

This study assessed pharmacokinetics and safety of subcutaneous (SC) belimumab in Chinese paediatric patients with systemic lupus erythematosus (cSLE) who previously received intravenous (IV) belimumab; only the IV form is approved for cSLE in China. This single-arm, open-label,...