Hubei University of Science and Technology

In-Situ Growth of Bimetallic ZnCo-ZIF-67 on Carbon Fibers as High-Efficiency Catalyst for Enhancing Thermal Decomposition of Ammonium Perchlorate

Due to its abundant active sites, the bimetallic zeolite imidazole framework ZnCo-ZIF-67 exhibits excellent catalytic performance on the key oxidant ammonium perchlorate in composite solid propellants. In addition, carbon fiber has been proven to promote the combustion of propell...

DARS2 Promotes Tumorigenesis and Metastasis by Activating PI3K / Akt / GSK ‐3β/β‐Catenin Signaling Pathway in Breast Cancer

ABSTRACT Aspartyl‐tRNA synthetase 2 (DARS2), the mitochondrial enzyme responsible for aminoacylation of aspartyl‐tRNA, is traditionally known for its effect on protein synthesis. Recently, DARS2 is reported to be implicated in tumorigenesis. However, its specific effect on breast...

Ubiquitination in cancer: mechanisms, signaling networks and potential therapeutic opportunities

Protein ubiquitination is among the most important posttranslational modifications in eukaryotes. It precisely regulates protein stability and cellular signaling through the ubiquitin‒proteasome system (UPS). A dynamic equilibrium network formed by the E1-E2-E3 enzymatic cascade...

A tributyrin-monolaurin complex protects piglets against PEDV infection via viral inhibition, lipid metabolism restoration, and microbiota modulation

Porcine epidemic diarrhea virus (PEDV) is a major pathogen causing severe diarrhea and intestinal damage in piglets. Monolaurin (GML) and tributyrin (TB) are well-documented functional lipids with intestinal health benefits, but their combined efficacy against PEDV infection rema...