Hubei Provincial Hospital of Traditional Chinese Medicine

Effects of various exercise interventions in adults with metabolic syndrome: a systematic review and network meta-analysis

Abstract Background Metabolic syndrome (MetS) is a major risk factor for type 2 diabetes mellitus and cardiovascular disease. This systematic review and network meta-analysis compared the effects of different exercise regimens on metabolic outcomes in adults with MetS. Methods Ra...

Community-based traditional Chinese medicine health service use among older adults and provider-reported delivery barriers in Wuhan, China: an explanatory sequential mixed-methods study

Population ageing and multimorbidity are increasing the need for accessible community-based care, while service use may vary according to service availability, affordability, and delivery capacity. In China, community-based traditional Chinese medicine (TCM) health services repre...

Breviscapine attenuates myocardial ischemia-reperfusion injury by inhibiting ferroptosis via activation of NRF2/SLC7A11/GPX4 pathway

To explore the protective effect of Breviscapine against myocardial ischemia-reperfusion (I/R) injury and its mechanism. The in vivo and in vitro models of myocardial I/R injury were first established and treated with different concentrations of Bre. The myocardial infarct size w...

Association between PSQI and composite endpoints in ALS patients: a retrospective cohort study from China

Abstract Background Sleep disturbance is common in patients with amyotrophic lateral sclerosis (ALS), but its association with severe clinical outcomes remains insufficiently characterized. We aimed to investigate the association between baseline sleep quality, assessed using the...

Association of C-reactive protein-triglycerides-glucose index-waist-to-height ratio with mortality in metabolic dysfunction-associated steatotic liver disease (MASLD): evidence from two cohort studies

Abstract Background MASLD significantly increases the risk of cardiovascular events and all-cause mortality (ACM). The impact of the C-reactive protein-triglyceride-glucose index (CTI) and its derivatives on mortality in the MASLD population remains unclear. This study aimed to i...

Ligament Advanced Reinforcement System (LARS) Augmented Repair vs Autograft Reconstruction for Chronic Lateral Ankle Instability: A Retrospective Comparative Study

BACKGROUND: Both autograft reconstruction and Ligament Advanced Reinforcement System (LARS) augmented repair are used for chronic ankle instability (CAI), but comparative evidence regarding postoperative recovery remains limited. This study compared recovery trajectories and func...

Mortality trends and geographic disparities in motor neuron disease among US adults aged 25 years and older, 1999–2024: a serial cross-sectional study using CDC WONDER

To examine long-term trends in mortality from motor neuron disease (MND) among adults aged 25 years and older in the United States from 1999 to 2024 using the CDC WONDER database, and to assess differences by demographic characteristics, geographic region, and urbanization level....

The association between a novel visceral lipoprotein risk index and new-onset diabetes in middle-aged and older Chinese adults

Abstract Background The global health burden of diabetes continues to grow. While the Chinese Visceral Adiposity Index (CVAI) and low-density lipoprotein cholesterol (LDL-C) are well-established risk factors for diabetes, the potential compounding effect of these factors is not w...

Anti-inflammatory mechanisms underlying sympathetic nervous system–mediated acupuncture analgesia

Sympathetic nerves play an important role in the generation and maintenance of pain, and many studies have shown that inflammatory factors play an important role in this process. During tissue inflammation or injury, the interaction between sympathetic nerves and the sensory nerv...

Neutrophil percentage-to-albumin ratio is associated with in-hospital mortality in patients with acute aortic dissection: a multicenter retrospective cohort study

Early risk stratification remains challenging in patients with acute aortic dissection (AAD). This study aims to evaluate the prognostic value of neutrophil percentage-to-albumin ratio (NPAR) for in-hospital mortality in patients with acute aortic dissection. We performed a multi...