Hubei Polytechnic University

Oil, light, gift, and trust: a comparative analysis of metaphor relating to human biomedical data

Abstract: This article analyzes four prevailing metaphors-”oil,” “light,” “gift,” and “trust”-that shape how human biomedical data are ethically and conceptually understood. Each metaphor reflects competing views on ownership, access, and responsibility. By comparing their streng...

Thermo-mechanical performance of a TiAlN-coated micro-drill: effect of cutting speed and point angle on tool wear, cutting forces, and surface integrity

Abstract Cobalt Chromium Molybdenum (CoCrMo) alloys are essential for biomedical applications. However, their high hardness and low thermal conductivity severely hinder machinability. In micro-drilling, a geometric trade-off typically exists, where smaller point angles improve pe...

Down-regulation of miR-23a-3p protects retinal pigment epithelial cells from oxidative stress via inducing SRC-3-mediated autophagy

Age-related macular degeneration is a main degenerative eye disease that eventually brings out irreversible vision loss. This study aimed to unmask miR-23a-3p’s role in AMD along with its underlying mechanism. Through MTT assay and flow cytomery analysis, H 2 O 2 -treated ARPE−19...

A bladder microenvironment-adaptive ceria nanozyme hydrogel enables urea-responsive intravesical chemo-immunotherapy

Bladder cancer intravesical therapy remains limited by rapid urinary washout, insufficient penetration across the bladder mucosal barrier, and an immunosuppressive tumor microenvironment. Here, we developed a bladder microenvironment-adaptive chemo-immunotherapy system, Gel/UCeNZ...