Huangshi Central Hospital

Down-regulation of miR-23a-3p protects retinal pigment epithelial cells from oxidative stress via inducing SRC-3-mediated autophagy

Age-related macular degeneration is a main degenerative eye disease that eventually brings out irreversible vision loss. This study aimed to unmask miR-23a-3p’s role in AMD along with its underlying mechanism. Through MTT assay and flow cytomery analysis, H 2 O 2 -treated ARPE−19...

A bladder microenvironment-adaptive ceria nanozyme hydrogel enables urea-responsive intravesical chemo-immunotherapy

Bladder cancer intravesical therapy remains limited by rapid urinary washout, insufficient penetration across the bladder mucosal barrier, and an immunosuppressive tumor microenvironment. Here, we developed a bladder microenvironment-adaptive chemo-immunotherapy system, Gel/UCeNZ...