Hualien Tzu Chi Medical Center

Development of multiplex real-time polymerase chain reaction assay for the detection of leukemia-associated translocation genes

A BSTRACT Objective: Leukemia diagnosis involves diverse methods, including cytomorphology, flow cytometry, cytogenetics, and molecular diagnostics. While cytogenetics plays an indispensable role, it is limited by a high false-negative rate. In contrast, molecular diagnostics, su...

Development and psychometric validation of the medical humanistic care scale

A BSTRACT Objectives: This study aimed to develop and validate the “Medical Humanistic Care Scale” (MHCS), a novel multidimensional instrument tailored to the Taiwanese healthcare education context. The scale addresses the limitations of existing tools by integrating social, inst...

Phytochemicals Modulating Receptor Tyrosine Kinase Signaling Networks in Endometriosis

Endometriosis is a chronic, estrogen-dependent inflammatory condition that is marked by the growth of lesions outside the uterus, along with angiogenesis, fibrosis, immune dysregulation, and pain sensitization. There is now growing evidence that receptor tyrosine kinase (RTK) sig...

Haplotype and copy number variation analysis of the MSTN gene associated with body size traits in three Tibetan sheep breeds

Under the constraints of ecological protection policies on the Qinghai-Tibet Plateau, the sheep industry must shift from quantitative expansion to meat yield improvement. Oula, Qiaoke, and Ganjia sheep are three Tibetan sheep breeds that exhibit significant differences in growth...

Longitudinal Immunophenotypic Changes in Refractory Lupus Nephritis After B-cell Depletion: A 25-year Case Study

Background/Aim: Long-term management of systemic lupus erythematosus (SLE) requires a persistent balance between intensive immunosuppression and the prevention of opportunistic infections. This is particularly challenging in patients with a multi-decade disease history and evolvi...

The effectiveness of resistance training for patients with degenerative arthritis after total joint arthroplasty: a pilot randomized controlled study

This study aimed to examine the effects of a volume-progressive staged bilateral resistance training program on lower limb muscular endurance, balance performance, pain intensity, and quality of life among patients with osteoarthritis following total joint arthroplasty (total kne...