Hospital Universitário Antônio Pedro

Real-world outcomes of CD34⁺ mobilization and early autologous hematopoietic stem cell transplantation recovery after daratumumab-based induction

INTRODUCTION: Daratumumab, an Anti-CD38 monoclonal antibody, is now widely used in frontline induction for transplant-eligible multiple myeloma. Although highly effective, concerns remain regarding its potential impact on CD34⁺ stem cell mobilization and early outcomes after auto...

Pharmacokinetic bioequivalence between (etonogestrel/ethinylestradiol 11.7/2.7 mg) NuvaRing ® and ornibel premium ® (etonogestrel/ethinylestradiol 8.25/2.6 mg), a novel polymer composition contraceptive vaginal ring

Objective This was a single-centre, randomised, single-ring insertion, 2-period, 2-sequence, crossover study designed to assess comparative bioavailability and thereby establish bioequivalence of two ethinylestradiol/etonogestrel vaginal rings (delivering 0.015/0.12 mg per day) a...

A Novel Radiographic Classification of the Proximal Tibiofibular Joint

Background and Objectives: We aim to develop a simple radiographic classification for describing the morphological inclination of the proximal tibiofibular joint (PTFJ) based on composite measurements obtained from standard anteroposterior and lateral knee radiographs, and to eva...