Hospital Sírio-Libanês

Real‐World HRR Testing Pathways and Patterns of Detected Alterations in Prostate Cancer From the Multinational ARON‐3 Study

ABSTRACT Background Homologous recombination repair (HRR) testing is increasingly relevant in prostate cancer because it identifies patients who may benefit from biomarker‐guided treatment strategies, including poly(ADP‐ribose) polymerase inhibitors (PARPi). However, real‐world i...

MR Neurography of Fine-Caliber Nerves: Technical Considerations and Practical Applications

With the advent of high-resolution imaging techniques, advanced fat and vascular suppression methods, and three-dimensional isotropic acquisitions, MR neurography of fine-caliber nerves has become an indispensable tool in assessment of peripheral neuropathies, but successful imag...

Circulating blood biomarkers after traumatic brain injury: A subanalysis of the biperiden phase III randomized, double‐blind clinical trial ( NCT01048138 )

OBJECTIVE: Traumatic brain injury (TBI) is a leading cause of acquired epilepsy, death, and long-term disability, yet reliable biomarkers to predict chronic sequelae such as post-traumatic epilepsy (PTE) remain limited. We evaluated the associations between circulating blood biom...

Global Real‐World Outcomes of Olaparib in Metastatic Castration‐Resistant Prostate Cancer Patients With Homologous Recombination Repair Alterations

Evidence to guide the treatment for patients with metastatic castration-resistant prostate cancer (mCRPC) and Homologous Recombination Repair (HRR) gene alterations outside of clinical trials remains limited. This was an observational, cohort study, including mCRPC patients with...

High‐Frequency Ultrasound Assessment of Female Genital Rejuvenation

Objectives To describe the role of high‐frequency ultrasound (HFUS) in the anatomical evaluation and monitoring of female genital rejuvenation procedures and to illustrate characteristic sonographic patterns associated with commonly used aesthetic treatments. Methods This retrosp...