Hospital Pablo Tobon Uribe

Cerebrospinal fluid cytochemical parameters as predictors of FilmArray Meningitis/Encephalitis panel positivity: a diagnostic stewardship approach in immunocompetent and immunocompromised patients

Infectious meningoencephalitis requires prompt diagnosis to reduce mortality and neurological sequelae. The FilmArray Meningitis/Encephalitis (FAME) panel has improved pathogen detection, but its indiscriminate use raises cost-effectiveness concerns. Because FAME is itself an imp...

Primary Repair Versus Pyloric Exclusion in Adult Traumatic Duodenal Injury: A Systematic Review and Meta‐Analysis With a Grade‐Restricted Analysis of AAST Grade III Injuries

ABSTRACT Background Whether pyloric exclusion ( PE ) retains any advantage over primary repair ( PR ) in adult traumatic duodenal injury is uncertain and confounded by indication. We restricted the comparison to the zone in which both techniques are realistically applicable. Meth...

Subnational Heterogeneity in RSV Seasonality in Tropical Colombia, 2022–2024

Abstract Background RSV transmission in tropical settings is often assumed to occur year-round, and preventive strategies are frequently recommended accordingly. However, sub-national variation in epidemic timing remains incompletely characterized. Granular local surveillance dat...

Obinutuzumab Induces Histological Remission and Deep Kidney Parenchymal B-Cell Depletion in Patients with Lupus Nephritis: Exploratory Analyses of the Phase III REGENCY Trial

Objectives The REGENCY trial ( NCT04221477 ) demonstrated superiority of obinutuzumab (OBI) plus standard therapy (+ST) vs placebo (PBO) +ST in achieving complete renal response (CRR) at Week 76 (W76) in adults with active lupus nephritis (LN). These exploratory analyses aimed to...

Psychometric properties of the Functional Assessment of Cancer Therapy–Lung (FACT-L) scale to measure health-related quality of life

Abstract Purpose To validate the Functional Assessment of Cancer Therapy–Lung (FACT-L) scale and assess its psychometric properties in patients with lung cancer in Colombia. Methods The analysis included exploratory and confirmatory factor analysis, internal consistency (248 pati...