Hospital Nacional de Niños

Persistent Varicella Transmission in a High-Coverage Single-Dose Vaccination Program: Costa Rica, 2015–2024

Background: Costa Rica introduced universal one-dose varicella vaccination in 2007 using a one-dose schedule administered at 15 months of age through the Costa Rican Social Security Fund (CCSS). A previous national study described epidemiological changes through 2014 by comparing...

A Structured Framework for Translation of the ACNS Standardized Critical Care EEG Terminology Into Spanish

Purpose: The American Clinical Neurophysiology Society (ACNS) Critical Care EEG Terminology provides standardized language for describing electroencephalographic (EEG) patterns in critically ill patients but has not been formally translated into Spanish. We aimed to develop a con...

Quality and concordance of international paediatric sepsis guidelines: a cross-sectional appraisal from the SENTINEL International study

Objectives To evaluate the methodological quality of hospital-specific paediatric sepsis clinical practice guidelines (CPGs) from sites participating in an international study using the Appraisal of Guidelines for Research and Evaluation II (AGREE II) tool and to assess the consi...

Physicochemical characterization, bioactive compounds, and antioxidant activities of tomato hybrids with resistance to Tomato yellow leaf curl virus (TYLCV)

A breeding program at the University of Costa Rica developed three tomato hybrids carrying tolerance to bacterial wilt and resistance genes (Ty) to Tomato yellow leaf curl virus (TYLCV). This study aimed to evaluate the physicochemical properties, carotenoid composition (HPLC-DAD...