Hospital Infantil de México Federico Gómez

Gut microbiota profile in school-aged children with vitamin A depletion and vitamin E deficiency: A cross-sectional study

Vitamin A (VitA) and vitamin E (VitE) deficiencies can result in significant health consequences in children. The role of the intestinal microbiota in these vitamin deficiencies has been scarcely explored. This cross-sectional study aimed to analyze the relationship of VitA deple...

First Reported Human Case of Primary Lymphocutaneous Nocardiosis Caused by Nocardia shinanonensis

Nocardia species are ubiquitous environmental microorganisms that can cause localized cutaneous, pulmonary or disseminated infections in humans. Primary cutaneous nocardiosis is uncommon and may present as cellulitis, abscesses, ulcers, granulomas or lymphocutaneous disease chara...

An international multicenter analysis of the outcome of pediatric first variceal hemorrhage

Background & Aims: Management of portal hypertension in children including primary prophylaxis of variceal bleeding is controversial due to limited understanding of mortality risk after first variceal hemorrhage (1VH). This international multicenter study was designed to advance...

Biocidal effect of UV-C light on environmental bacteria in a Neonatal Intensive Care Unit

Abstract Background Germicidal irradiation with Ultra-Violet light type C (UV-C) (UV-C=200-280 nm) is used as a complement to hospital cleaning in health centers to disinfect air and surfaces, eliminating up to 99.9999% (-6 logarithms) of viruses and bacteria. Standard cleaning i...

FAK regulates leptin-induced angiogenesis and vasculogenic mimicry in breast cancer

Abstract Leptin, an adipokine primarily secreted by adipose tissue, has been implicated in tumor progression by regulating angiogenesis. Leptin also plays a key role in tumor vascularization by promoting vasculogenic mimicry (VM). During tumor progression, leptin activates severa...

Optimizing Empirical Antibiotic Therapy in Febrile Pediatric Oncology Patients through a Clinical Decision Pathway

Abstract Background Timely management of a child with cancer and fever (CCF) requires accurate evaluation and appropriate antibiotic selection to prevent infectious complications. Clinical decision tools, such as Clinical Decision Pathways (CDPs), are increasingly adopted in heal...

Maternal Dietary B-Complex Vitamin Pattern and Risk of Complex Congenital Heart Defects in a Mexican Population

Background/Objectives: Congenital heart defects (CHDs) are among the most common congenital anomalies worldwide, and maternal nutrition during early pregnancy may influence their development. Although previous studies have mainly evaluated individual B-complex vitamins, the contr...

Impact of Coffee Consumption on Fructose-Related Metabolic Alterations: Potential Mechanisms and Implications for Metabolic Diseases

Coffee is one of the most widely consumed beverages worldwide. Coffee and its bioactive compounds, including caffeine, chlorogenic acid, and caffeic acid, have attracted increasing attention because of their potential health benefits. Evidence from pediatric and adult populations...