Hospital de Viladecans

Interference by macro-B12: multicenter evaluation of polyethylene glycol precipitation and establishment of reference intervals using four different immunoassay methods

Abstract Objectives Macro-B12 interference is an underestimated cause of hypercobalaminemia that may lead to misleading clinical interpretations. The aims of this study were to evaluate the diagnostic performance of polyethylene glycol (PEG) precipitation for the detection of mac...

Predicting SILENT after lithium poisoning: a multicenter cohort study and pragmatic risk stratification model

INTRODUCTION: The Syndrome of Irreversible Lithium-Effectuated Neurotoxicity (SILENT) is a rare but potentially devastating complication of lithium poisoning. Current evidence rests on case reports and small series, leaving its true incidence, risk factors, and follow-up tools po...