Institution
Hospital das Clínicas da Universidade Federal de Minas Gerais
Recent research
- BiologyOpen access
Objective To critically review the available evidence on the pathophysiology and diagnosis of Menière’s disease and to provide consensus-based recommendations developed by a task force of the Brazilian Society of Otology and the Brazilian Academy of Neurotology. Methods A task fo...
- Health & MedicineOpen access
Identifying Cardiac Autoantibody Biomarkers that Predict the Severity of Chagas Cardiomyopathy
Chagas cardiomyopathy (ChCM) affects up to 30% of patients with chronic Chagas disease and lacks reliable biomarkers for severity and conduction abnormalities. We profiled cardiac autoantibodies using 2-dimensional gel electrophoresis and mass spectrometry, followed by enzyme-lin...
- Health & Medicine
An international multicenter analysis of the outcome of pediatric first variceal hemorrhage
Background & Aims: Management of portal hypertension in children including primary prophylaxis of variceal bleeding is controversial due to limited understanding of mortality risk after first variceal hemorrhage (1VH). This international multicenter study was designed to advance...
- BiologyOpen access
Objectives We conducted a randomized, double-masked, multicenter clinical trial to evaluate the incremental effect of leucine (LEU)-enriched chocolate supplementation (7.5 g of LEU/d for 12 wk) in addition to an active nutrition intervention on muscle strength in patients undergo...
- Climate & EnvironmentOpen access
The annual cycle activities of birds from Serra da Mantiqueira, Brazil
Abstract The timing of feather molting and breeding, two key activities in the avian life cycle, varies widely among species. These variations are shaped by each species’ unique ecological traits and their interactions with dissimilar environmental factors, such as seasonal chang...
- Health & MedicineOpen access
Contrastive learning is a widely adopted self-supervised pretraining strategy, yet its dependence on cohort composition remains underexplored. We present Contrasting by Augmented Patient Electrocardiograms (CAPE) foundation model and pretrain on four cohorts (n = 5,203,269), from...
- Health & MedicineOpen access
BACKGROUND: The management of decompensated autoimmune hepatitis (AIH) cirrhosis is one of the most challenging and controversial scenarios in hepatology. Clinicians face a high-stakes dilemma: whether to initiate immunosuppression to halt inflammatory activity or prioritize live...