Hôpital Pontchaillou

Technical Refinements in Brain-dead Donor Uterus Transplantation: Lessons From the 3 First Cases in France.

Background: Uterus procurement from brain-dead donors during multiorgan procurement for uterus transplantation (UTx) presents a technical challenge because the uterus is not a vital organ and also because of the need to harvest uterine and ovarian veins for transplantation. The a...

Paraneoplastic podocytopathies with nephrotic syndrome in solid cancers with C-Maf Inducing Protein expression

Abstract Background The main features of minimal change disease (MCD) and focal segmental glomerulosclerosis (FSGS) associated with solid cancer (paraneoplastic podocytopathy with nephrotic syndrome, PPNS) remain poorly described. Methods In this French retrospective study, we fo...

Lenalidomide maintenance after initial immunochemotherapy in chronic lymphocytic leukaemia—Final analysis of the international phase III CLL6 RESIDUUM study of the ALLG and FILO groups

Summary Most patients treated for chronic lymphocytic leukaemia (CLL) fail to achieve measurable residual disease (MRD) negativity. The role of maintenance with the immunomodulatory drug lenalidomide in these patients is unclear. A randomised multicentre phase III trial (ACTRN126...

A single-cell atlas of large B cell lymphomas reveals distinct malignant archetypes predictive of clinical outcomes

Large B cell lymphomas (LBCLs) exhibit significant heterogeneity which leads to disparate treatment response, with up to 40% of patients developing refractory disease or relapsing within the first two years. To understand the cellular and molecular basis of this heterogeneity, we...

Anesthesia TeleConsultation for Pediatric preoperative assessment: a large national prospective multicentric study in children (TeleCCCAP)

Background: While interest in pediatric anesthesia teleconsultation is growing, published data remain scarce. This study evaluated the feasibility of anesthesia teleconsultation in children, providing a comprehensive analysis of failure, quality, dedicated time and satisfaction....